新试验发现首个减缓阿尔茨海默病对病人大脑损伤的药物,这个名为 lecanemab 的药物 意义重大。这项试验的结果为此范围几十年的高失败率画上句号,并表明用药物治疗阿尔茨海默病(最容易见到的失智症)的新年代并不是遥不可及。
News of the first drug that can slow the progression of Alzheimers has been called historic and prompted huge excitement among researchers and charities. The manufacturer said it would be filing for regulatory approval in January and hope lecanemab may be available from September in the UK.
首个能减缓阿尔茨海默病病程的药物的试验结果被叫做是 有历史意义的,这个消息哄动了业界的研究职员和慈善机构。该药物的制造商表示将于明年1月向监管机构提交申请,并期望 lecanemab 能从明年9月起在英国上市。
Lecanemab is a monoclonal antibody. These are cosplaytly to produce in the lab, so will inevitably be an expensive product. It is only suitable for those with early|stage Alzheimers, but few patients in the UK have the confirmatory diagnostic test needed to show they could benefit from the drug. So, its use could be very limited at first, and patients will have to be carefully monitored for side effects.
Lecanemab 是一种单克隆抗体。在实验室生产该抗体的本钱非常高,因此它势必是一种昂贵的药品。该药只适用于治疗早期阿尔茨海默病的病人,但在英国,极少有病人有证实性诊断测试结果,表明他们能从这种药物中获益。因此,起初该药物的用法可能很有限,而且研究职员需要仔细监测服药对病人身体产生的不良反应。